‘Tumors just vanished’: Cancer patients now in remission after drug trial – CNN
A group of patients with rectal cancer entered a study thinking they would have to undergo grueling treatments but were surprised when they were told their tumors had disappeared.
None of the patients had clinically significant complications from a drug used to treat cancer. The medication was given every three weeks for six months and cost about $11,000 per dose.
Dr. Hanna K. Sanoff, who was not involved in the study, called it “small but compelling,” but added that it is not clear if the patients are cured.
A clinical trial led by Diaz in 2017 that involved 86 people with metastatic cancer that originated in various parts of their bodies inspired Cercek and Diaz to study patients with locally advanced rectal cancer. They found that patients with a gene mutation that prevented cells from repairing damage to DNA responded well to treatment.
Diaz and Cercek began asking companies that made checkpoint inhibitors if they would sponsor a small trial. The companies said the trial was too risky, but a small biotechnology firm, Tesaro, agreed to sponsor the trial.
Sascha Roth, 38, was diagnosed with rectal cancer and told to start chemotherapy. A friend insisted she first see Dr. Philip Paty at Memorial Sloan Kettering, who said she could enter a clinical trial.
Roth had her ovaries removed and put back under her ribs after the trial ended, but two years later she still has no trace of cancer.
For more on this story, please consider these sources:
- ‘Tumors just vanished’: Cancer patients now in remission after drug trial CNN
- A Cancer Trial’s Unexpected Result: Remission in Every Patient Yahoo! Voices
- NYC Cancer Trial Delivers ‘Unheard-of’ Result: Complete Remission for Everyone NBC New York
- ‘Remarkable’ Cancer Treatment Study Shows Stunning Results: ‘The First Time This Has Happened’ CBN.com
- Experimental rectal cancer drug caused all patients’ tumors to disappear in small trial Livescience.com
- View Full Coverage on Google News