St. Louis, Missouri – A recent study reveals a concerning trend in the rise of cancer cases among younger adults, indicating a potential link to accelerated biological aging. Researchers delving into the reasons behind this increase suggest that aging is a significant risk factor for various types of cancer, emphasizing the importance of considering biological age alongside chronological age.
Dr. Yin Cao, an associate professor at Washington University School of Medicine in St. Louis, led the study that analyzed medical records of over 148,000 individuals aged 37 to 54. The research focused on nine blood-based markers associated with biological age, such as albumin, creatinine, and glucose, among others.
Using an algorithm called PhenoAge, the researchers calculated each person’s biological age and compared it to their chronological age to determine accelerated aging. The study found that individuals born after 1965 were 17% more likely to exhibit accelerated aging than those born between 1950 and 1954.
Furthermore, the research linked accelerated aging to an increased risk of cancer, particularly lung, stomach, intestinal, and uterine cancers. Individuals showing signs of faster aging had significantly higher risks of developing these types of cancer at a younger age.
While the study did not explore the specific reasons for these strong connections between cancer and accelerated aging, researchers believe that factors such as tissue vulnerability, inflammation, and genetic predispositions may play a role. Additionally, the study emphasized the need for further exploration in diverse populations to understand the impact of social factors on cancer risk.
Dr. Anne Blaes, a researcher at the University of Minnesota, highlighted the implications of the study’s findings in identifying individuals at higher risk for cancer at a younger age. By targeting lifestyle interventions and exploring potential medications to counter accelerated aging, there may be opportunities to improve cancer prevention strategies for young adults.
The study’s outcomes underscore the importance of considering biological age as a critical factor in understanding cancer risks and developing personalized screening and intervention approaches. As research in this area continues to evolve, there is hope for more effective strategies to address the growing incidence of cancer among younger populations.