Iron Deficiency Linked to Lingering COVID Fatigue: New Study Uncovers Surprising Culprit

Cambridge, England – Long COVID, a persistent collection of symptoms experienced by millions of individuals post-recovery from COVID, has been linked to low iron levels in a recent study conducted by the University of Cambridge. Iron, an essential mineral for various bodily functions, plays a crucial role in the production of hemoglobin, which transports oxygen in the blood.

While sources of iron can be obtained from both plant and animal foods, the absorption of non-heme iron from plant-based sources is less efficient compared to heme iron found in animal products. The disruption in iron management caused by COVID can lead to conditions like iron deficiency or abnormal iron storage, impacting the severity of the infection and affecting the recovery process.

A study involving 214 individuals revealed specific characteristics of long-term COVID-19, including continued inflammation and signs of anemia for up to a year after the initial infection. Anemia, characterized by a deficiency in red blood cells, can result in fatigue and weakness due to insufficient oxygen reaching the body’s tissues. The persistent inflammation indicates continued activity of the immune system even after the primary infection has resolved.

Researchers discovered abnormal iron levels and changes in genes related to iron management in individuals with long COVID, suggesting a potential imbalance in how the body handles iron post-infection. The study also highlighted a process called “stress erythropoiesis” in long COVID patients, where the body tries to produce more red blood cells in response to stress or inflammation but may not be as effective following a COVID-19 infection.

Symptoms of long COVID can be wide-ranging, including extreme fatigue, difficulty concentrating, shortness of breath, chest pain, heart problems, muscle and joint pain, loss of taste or smell, sleep disturbances, mood swings, and digestive issues. Post-exertional malaise, where symptoms worsen after physical or mental activities, can also make daily activities challenging for individuals with long COVID.

For those experiencing long COVID, seeking medical evaluation, managing symptoms, considering rehabilitation programs, maintaining a balanced diet, seeking mental health support, pacing activities to manage energy levels, and staying informed about new developments in treatment options are essential steps. With ongoing research in the field of long COVID, personalized approaches to managing symptoms and improving quality of life are crucial for individuals affected by this condition.